Identification of novel viruses in Amblyomma americanum, Dermacentor variabilis, and Ixodes scapularis ticks
Department(s)
Natural Science
Document Type
Article
Publication Date
3-1-2018
Keywords
I. scapularis, Ticks, Virome
Abstract
Ticks carry a wide range of known human and animal pathogens and are postulated to carry others with the potential to cause disease. Here we report a discovery effort wherein unbiased high-throughput sequencing was used to characterize the virome of 2,021 ticks, including Ixodes scapularis (n = 1,138), Amblyomma americanum (n = 720), and Dermacentor variabilis (n = 163), collected in New York, Connecticut, and Virginia in 2015 and 2016. We identified 33 viruses, including 24 putative novel viral species. The most frequently detected viruses were phylogenetically related to members of the Bunyaviridae and Rhabdoviridae families, as well as the recently proposed Chuviridae. Our work expands our understanding of tick viromes and underscores the high viral diversity that is present in ticks.
Publication Title
mSphere
E-ISSN
23795042
Volume
3
Issue
2
DOI
10.1128/mSphere.00614-17
PubMed ID
29564401
Recommended Citation
Tokarz, Rafal; Sameroff, Stephen; Tagliafierro, Teresa; Jain, Komal; Williams, Simon H.; Cucura, D. Moses; Rochlin, Ilia; Monzon, Javier; Carpi, Giovanna; Tufts, Danielle; Diuk-Wasser, Maria; Brinkerhoff, Jory; and Lipkin, W. Ian, "Identification of novel viruses in Amblyomma americanum, Dermacentor variabilis, and Ixodes scapularis ticks" (2018). Pepperdine University, All Faculty Open Access Publications. Paper 88.
https://digitalcommons.pepperdine.edu/faculty_pubs/88