Presentation Title

Application of microwave-assisted extraction of oleandrin from Nerium oleander coupled with purification with using divalent metal ion-loaded cation exchange resins

Presentation Type

Poster

Department

Chemistry

Major

Chemistry

Abstract

Oleandrin, from Nerium oleander, is a toxic cardiac glycoside also known for its medical and toxicological properties that make it useful in treating heart failure and cardiac arrhythmia. We have developed a new class of supported-metal ion solid-phase extraction resins to isolate oleandrin in high purity from N. oleander, utilizing fewer and less hazardous solvents over published liquid-liquid extraction methods. In addition, we have applied microwave-assisted techniques to further reduce the time and volume of reagents necessary to extract the crude oleandrin from the plant tissue, with quantitative recovery after isolation with our modified resins.

Faculty Mentor

Dr. David Green

Location

Waves Cafeteria

Start Date

1-4-2016 2:00 PM

End Date

1-4-2016 3:00 PM

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Application of microwave-assisted extraction of oleandrin from Nerium oleander coupled with purification with using divalent metal ion-loaded cation exchange resins

Waves Cafeteria

Oleandrin, from Nerium oleander, is a toxic cardiac glycoside also known for its medical and toxicological properties that make it useful in treating heart failure and cardiac arrhythmia. We have developed a new class of supported-metal ion solid-phase extraction resins to isolate oleandrin in high purity from N. oleander, utilizing fewer and less hazardous solvents over published liquid-liquid extraction methods. In addition, we have applied microwave-assisted techniques to further reduce the time and volume of reagents necessary to extract the crude oleandrin from the plant tissue, with quantitative recovery after isolation with our modified resins.